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After excluding the duplicated, irrelevant, and no full-text-available articles, we included 156 studies in this narrative review

REDEFINE 2 (Type 2 Diabetes) In patients with T2D, CagriSema produced significant weight loss alongside glycemic improvements (HbA1c reduction), outperforming the individual components (Lingvay et al., 2025)

There is no conclusive evidence to indicate that n-3 PUFAs exert positive effects and n-6 PUFAs exert negative effects or that the dietary n-6:n-3 PUFA ratio influences the prevalence of asthma in adults (258)

Supplemental Table 2

Brief breaks preventing cumulative strain prove more effective than longer breaks after damage accumulates